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COL25A1 triggers and promotes Alzheimer’s disease-like pathology in vivo

Collagen XXV alpha 1 (COL25A1) is a collagenous type II transmembrane protein purified from senile plaques of Alzheimer’s disease (AD) brains. COL25A1 alleles have been associated with increased risk for AD in a Swedish population. COL25A1 is specifically expressed in neurons and binds to aggregated...

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Detalles Bibliográficos
Autores principales: Tong, Ying, Xu, Ying, Scearce-Levie, Kimberly, Ptáček, Louis J., Fu, Ying-Hui
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807601/
https://www.ncbi.nlm.nih.gov/pubmed/19548013
http://dx.doi.org/10.1007/s10048-009-0201-5