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Dexamethasone disrupts intercellular junction formation and cytoskeleton organization in human trabecular meshwork cells

PURPOSE: Patients reproduce symptoms of primary open-angle glaucoma (POAG) when treated with glucocorticoids (GCs) topically on the eyes. Here we investigated the effects of GCs on junctional protein expression and cytoskeleton organization in primary human trabecular meshwork (TM) cultures to under...

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Detalles Bibliográficos
Autores principales: Zhuo, Ye Hong, He, Yuan, Leung, Kar Wah, Hou, Fei, Li, Yi Qing, Chai, Fang, Ge, Jian
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807616/
https://www.ncbi.nlm.nih.gov/pubmed/20090922