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Regulation of oligodendrocyte progenitor cell maturation by PPARδ: effects on bone morphogenetic proteins

In EAE (experimental autoimmune encephalomyelitis), agonists of PPARs (peroxisome proliferator-activated receptors) provide clinical benefit and reduce damage. In contrast with PPARγ, agonists of PPARδ are more effective when given at later stages of EAE and increase myelin gene expression, suggesti...

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Detalles Bibliográficos
Autores principales: Vittoria Simonini, Maria, Polak, Paul E, Boullerne, Anne I, Peters, Jeffrey M, Richardson, Jill C, Feinstein, Douglas L
Formato: Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807733/
https://www.ncbi.nlm.nih.gov/pubmed/20001953
http://dx.doi.org/10.1042/AN20090033