Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors

BACKGROUND: The Fanconi anemia (FA) pathway is a multigene DNA damage response network implicated in the repair of DNA lesions that arise during replication or after exogenous DNA damage. The FA pathway displays synthetic lethal relationship with certain DNA repair genes such as ATM (Ataxia Telangec...

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Detalles Bibliográficos
Autores principales: Landais, Igor, Hiddingh, Sanne, McCarroll, Matthew, Yang, Chao, Sun, Aiming, Turker, Mitchell S, Snyder, James P, Hoatlin, Maureen E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807854/
https://www.ncbi.nlm.nih.gov/pubmed/20043851
http://dx.doi.org/10.1186/1476-4598-8-133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807854/
https://www.ncbi.nlm.nih.gov/pubmed/20043851
http://dx.doi.org/10.1186/1476-4598-8-133

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