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Identification of mammalian orthologs using local synteny

BACKGROUND: Accurate determination of orthology is central to comparative genomics. For vertebrates in particular, very large gene families, high rates of gene duplication and loss, multiple mechanisms of gene duplication, and high rates of retrotransposition all combine to make inference of ortholo...

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Detalles Bibliográficos
Autores principales: Jun, Jin, Mandoiu, Ion I, Nelson, Craig E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807883/
https://www.ncbi.nlm.nih.gov/pubmed/20030836
http://dx.doi.org/10.1186/1471-2164-10-630