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Rab5 Mediates Caspase-8–promoted Cell Motility and Metastasis

Caspase-8 is a key apical sensory protein that governs cell responses to environmental cues, alternatively promoting apoptosis, proliferation, and cell migration. The proteins responsible for integration of these pathways, however, have remained elusive. Here, we reveal that Rab5 regulates caspase-8...

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Detalles Bibliográficos
Autores principales: Torres, Vicente A., Mielgo, Ainhoa, Barbero, Simone, Hsiao, Ruth, Wilkins, John A., Stupack, Dwayne G.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808229/
https://www.ncbi.nlm.nih.gov/pubmed/19923319
http://dx.doi.org/10.1091/mbc.E09-09-0769