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Rab5 Mediates Caspase-8–promoted Cell Motility and Metastasis
Caspase-8 is a key apical sensory protein that governs cell responses to environmental cues, alternatively promoting apoptosis, proliferation, and cell migration. The proteins responsible for integration of these pathways, however, have remained elusive. Here, we reveal that Rab5 regulates caspase-8...
Autores principales: | Torres, Vicente A., Mielgo, Ainhoa, Barbero, Simone, Hsiao, Ruth, Wilkins, John A., Stupack, Dwayne G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808229/ https://www.ncbi.nlm.nih.gov/pubmed/19923319 http://dx.doi.org/10.1091/mbc.E09-09-0769 |
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