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Mycobacterial Nucleoside Diphosphate Kinase Blocks Phagosome Maturation in Murine Raw 264.7 Macrophages

BACKGROUND: Microorganisms capable of surviving within macrophages are rare, but represent very successful pathogens. One of them is Mycobacterium tuberculosis (Mtb) whose resistance to early mechanisms of macrophage killing and failure of its phagosomes to fuse with lysosomes causes tuberculosis (T...

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Detalles Bibliográficos
Autores principales: Sun, Jim, Wang, Xuetao, Lau, Alice, Liao, Ting-Yu Angela, Bucci, Cecilia, Hmama, Zakaria
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808246/
https://www.ncbi.nlm.nih.gov/pubmed/20098737
http://dx.doi.org/10.1371/journal.pone.0008769