Hypothalamic-Specific Manipulation of Fto, the Ortholog of the Human Obesity Gene FTO, Affects Food Intake in Rats

Sequence variants in the first intron of FTO are strongly associated with human obesity and human carriers of the risk alleles show evidence for increased appetite and food intake. Mice globally lacking Fto display a complex phenotype characterised by both increased energy expenditure and increased...

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Detalles Bibliográficos
Autores principales: Tung, Yi-Chun Loraine, Ayuso, Eduard, Shan, Xiaoye, Bosch, Fatima, O'Rahilly, Stephen, Coll, Anthony P., Yeo, Giles S. H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808248/
https://www.ncbi.nlm.nih.gov/pubmed/20098739
http://dx.doi.org/10.1371/journal.pone.0008771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808248/
https://www.ncbi.nlm.nih.gov/pubmed/20098739
http://dx.doi.org/10.1371/journal.pone.0008771

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