Cargando…
Prediction of calcium-binding sites by combining loop-modeling with machine learning
BACKGROUND: Protein ligand-binding sites in the apo state exhibit structural flexibility. This flexibility often frustrates methods for structure-based recognition of these sites because it leads to the absence of electron density for these critical regions, particularly when they are in surface loo...
Autores principales: | , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808310/ https://www.ncbi.nlm.nih.gov/pubmed/20003365 http://dx.doi.org/10.1186/1472-6807-9-72 |