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Gain in cellular organization of inflammatory breast cancer: A 3D in vitro model that mimics the in vivo metastasis
BACKGROUND: The initial step of metastasis in carcinomas, often referred to as the epithelial-mesenchymal transition (EMT), occurs via the loss of adherens junctions (e.g. cadherins) by the tumor embolus. This leads to a subsequent loss of cell polarity and cellular differentiation and organization,...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808321/ https://www.ncbi.nlm.nih.gov/pubmed/20028562 http://dx.doi.org/10.1186/1471-2407-9-462 |