Improving the efficiency of genomic loci capture using oligonucleotide arrays for high throughput resequencing

BACKGROUND: The emergence of next-generation sequencing technology presents tremendous opportunities to accelerate the discovery of rare variants or mutations that underlie human genetic disorders. Although the complete sequencing of the affected individuals' genomes would be the most powerful...

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Detalles Bibliográficos
Autores principales: Lee, Hane, O'Connor, Brian D, Merriman, Barry, Funari, Vincent A, Homer, Nils, Chen, Zugen, Cohn, Daniel H, Nelson, Stanley F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Methodology article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808330/
https://www.ncbi.nlm.nih.gov/pubmed/20043857
http://dx.doi.org/10.1186/1471-2164-10-646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808330/
https://www.ncbi.nlm.nih.gov/pubmed/20043857
http://dx.doi.org/10.1186/1471-2164-10-646

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