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A Novel Alignment-Free Method for Comparing Transcription Factor Binding Site Motifs

BACKGROUND: Transcription factor binding site (TFBS) motifs can be accurately represented by position frequency matrices (PFM) or other equivalent forms. We often need to compare TFBS motifs using their PFMs in order to search for similar motifs in a motif database, or cluster motifs according to th...

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Detalles Bibliográficos
Autores principales: Xu, Minli, Su, Zhengchang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808352/
https://www.ncbi.nlm.nih.gov/pubmed/20098703
http://dx.doi.org/10.1371/journal.pone.0008797