Functional Exploration of the Adult Ovarian Granulosa Cell Tumor-Associated Somatic FOXL2 Mutation p.Cys134Trp (c.402C>G)

BACKGROUND: The somatic mutation in the FOXL2 gene c.402C>G (p.Cys134Trp) has recently been identified in the vast majority of adult ovarian granulosa cell tumors (OGCTs) studied. In addition, this mutation seems to be specific to adult OGCTs and is likely to be a driver of malignant transformati...

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Detalles Bibliográficos
Autores principales: Benayoun, Bérénice A., Caburet, Sandrine, Dipietromaria, Aurélie, Georges, Adrien, D'Haene, Barbara, Pandaranayaka, P. J. Eswari, L'Hôte, David, Todeschini, Anne-Laure, Krishnaswamy, Sankaran, Fellous, Marc, De Baere, Elfride, Veitia, Reiner A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808356/
https://www.ncbi.nlm.nih.gov/pubmed/20098707
http://dx.doi.org/10.1371/journal.pone.0008789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808356/
https://www.ncbi.nlm.nih.gov/pubmed/20098707
http://dx.doi.org/10.1371/journal.pone.0008789

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