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Endogenous Morphine Levels Are Increased in Sepsis: A Partial Implication of Neutrophils

BACKGROUND: Mammalian cells synthesize morphine and the respective biosynthetic pathway has been elucidated. Human neutrophils release this alkaloid into the media after exposure to morphine precursors. However, the exact role of endogenous morphine in inflammatory processes remains unclear. We post...

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Detalles Bibliográficos
Autores principales: Glattard, Elise, Welters, Ingeborg D., Lavaux, Thomas, Muller, Arnaud H., Laux, Alexis, Zhang, Dan, Schmidt, Alexander R., Delalande, François, Laventie, Benoît-Joseph, Dirrig-Grosch, Sylvie, Colin, Didier A., Van Dorsselaer, Alain, Aunis, Dominique, Metz-Boutigue, Marie-Hélène, Schneider, Francis, Goumon, Yannick
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808358/
https://www.ncbi.nlm.nih.gov/pubmed/20098709
http://dx.doi.org/10.1371/journal.pone.0008791