JS-K, a Nitric Oxide Prodrug, Has Enhanced Cytotoxicity in Colon Cancer Cells with Knockdown of Thioredoxin Reductase 1

BACKGROUND: The selenoenzyme thioredoxin reductase 1 has a complex role relating to cell growth. It is induced as a component of the cellular response to potentially mutagenic oxidants, but also appears to provide growth advantages to transformed cells by inhibiting apoptosis. In addition, selenocys...

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Detalles Bibliográficos
Autores principales: Edes, Kornelia, Cassidy, Pamela, Shami, Paul J., Moos, Philip J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808390/
https://www.ncbi.nlm.nih.gov/pubmed/20098717
http://dx.doi.org/10.1371/journal.pone.0008786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808390/
https://www.ncbi.nlm.nih.gov/pubmed/20098717
http://dx.doi.org/10.1371/journal.pone.0008786

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