In vitro evaluation of pan-PI3-kinase inhibitor SF1126 in trastuzumab-sensitive and trastuzumab-resistant HER2-over-expressing breast cancer cells

PURPOSE: The purpose of the current study is to determine the in vitro cytotoxic effects of the novel pan-PI3-kinase inhibitor SF1126 in HER2-over-expressing breast cancer cells. METHODS: Cell proliferation and cytotoxicity were examined by MTS colorimetric assay, FACS analysis, colony formation ass...

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Detalles Bibliográficos
Autores principales: Ozbay, Tuba, Durden, Donald L., Liu, Tongrui, O’Regan, Ruth M., Nahta, Rita
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808522/
https://www.ncbi.nlm.nih.gov/pubmed/19636556
http://dx.doi.org/10.1007/s00280-009-1075-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808522/
https://www.ncbi.nlm.nih.gov/pubmed/19636556
http://dx.doi.org/10.1007/s00280-009-1075-9

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