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In vitro evaluation of pan-PI3-kinase inhibitor SF1126 in trastuzumab-sensitive and trastuzumab-resistant HER2-over-expressing breast cancer cells
PURPOSE: The purpose of the current study is to determine the in vitro cytotoxic effects of the novel pan-PI3-kinase inhibitor SF1126 in HER2-over-expressing breast cancer cells. METHODS: Cell proliferation and cytotoxicity were examined by MTS colorimetric assay, FACS analysis, colony formation ass...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808522/ https://www.ncbi.nlm.nih.gov/pubmed/19636556 http://dx.doi.org/10.1007/s00280-009-1075-9 |