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Evaluation of the exposure equivalence of oral versus intravenous temozolomide

PURPOSE: Oral temozolomide is approved in many countries for malignant glioma and for melanoma in some countries outside the USA. This study evaluated the exposure equivalence and safety of temozolomide by intravenous infusion and oral administration. METHODS: Subjects with primary central nervous s...

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Detalles Bibliográficos
Autores principales: Diez, Blanca D., Statkevich, Paul, Zhu, Yali, Abutarif, Malaz A., Xuan, Fengjuan, Kantesaria, Bhavna, Cutler, David, Cantillon, Marc, Schwarz, Max, Pallotta, Maria Guadalupe, Ottaviano, Fabio H.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808524/
https://www.ncbi.nlm.nih.gov/pubmed/19641919
http://dx.doi.org/10.1007/s00280-009-1078-6