Cargando…
Evaluation of the exposure equivalence of oral versus intravenous temozolomide
PURPOSE: Oral temozolomide is approved in many countries for malignant glioma and for melanoma in some countries outside the USA. This study evaluated the exposure equivalence and safety of temozolomide by intravenous infusion and oral administration. METHODS: Subjects with primary central nervous s...
Autores principales: | Diez, Blanca D., Statkevich, Paul, Zhu, Yali, Abutarif, Malaz A., Xuan, Fengjuan, Kantesaria, Bhavna, Cutler, David, Cantillon, Marc, Schwarz, Max, Pallotta, Maria Guadalupe, Ottaviano, Fabio H. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808524/ https://www.ncbi.nlm.nih.gov/pubmed/19641919 http://dx.doi.org/10.1007/s00280-009-1078-6 |
Ejemplares similares
-
Comparison of the systemic bioavailability of mometasone furoate after oral inhalation from a mometasone furoate/formoterol fumarate metered-dose inhaler versus a mometasone furoate dry-powder inhaler in patients with chronic obstructive pulmonary disease
por: Kosoglou, Teddy, et al.
Publicado: (2013) -
Phase I dose-escalation and pharmacokinetic study of temozolomide (SCH 52365) for refractory or relapsing malignancies
por: Brada, M, et al.
Publicado: (1999) -
Marked inactivation of O(6)-alkylguanine-DNA alkyltransferase activity with protracted temozolomide schedules
por: Tolcher, A W, et al.
Publicado: (2003) -
Developing a Natural History Progression Model for Duchenne Muscular Dystrophy Using the Six‐Minute Walk Test
por: Hamuro, Lora, et al.
Publicado: (2017) -
Accelerated hyperfractionated radiochemotherapy with temozolomide is equivalent to normofractionated radiochemotherapy in a retrospective analysis of patients with glioblastoma
por: Lewitzki, Victor, et al.
Publicado: (2019)