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Chemical reprogramming of Caenorhabditis elegans germ cell fate

Small-molecules can control cell fate in vivo and may allow directed induction of desired cell types, providing an attractive alternative to transplant-based approaches in regenerative medicine. We have chemically induced functional oocytes in C. elegans adults that otherwise produced only sperm. Th...

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Detalles Bibliográficos
Autores principales: Morgan, Clinton T., Lee, Myon-Hee, Kimble, Judith
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808631/
https://www.ncbi.nlm.nih.gov/pubmed/20081824
http://dx.doi.org/10.1038/nchembio.282