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Algorithms for locating extremely conserved elements in multiple sequence alignments

BACKGROUND: In 2004, Bejerano et al. announced the startling discovery of hundreds of "ultraconserved elements", long genomic sequences perfectly conserved across human, mouse, and rat. Their announcement stimulated a flurry of subsequent research. RESULTS: We generalize the notion of ultr...

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Detalles Bibliográficos
Autores principales: Tseng, Huei-Hun E, Tompa, Martin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808710/
https://www.ncbi.nlm.nih.gov/pubmed/20021665
http://dx.doi.org/10.1186/1471-2105-10-432