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MNAzymes, a Versatile New Class of Nucleic Acid Enzymes That Can Function as Biosensors and Molecular Switches

[Image: see text] To increase the versatility and utility of nucleic acid enzymes, we developed multicomponent complexes, known as MNAzymes, which produce amplified “output” signals in response to specific “input” signals. Multiple oligonucleotide partzymes assemble into active MNAzymes only in the...

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Detalles Bibliográficos
Autores principales: Mokany, Elisa, Bone, Simon M., Young, Paul E., Doan, Tram B., Todd, Alison V.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808728/
https://www.ncbi.nlm.nih.gov/pubmed/20038095
http://dx.doi.org/10.1021/ja9076777