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SelTarbase, a database of human mononucleotide-microsatellite mutations and their potential impact to tumorigenesis and immunology

About 15% of human colorectal cancers and, at varying degrees, other tumor entities as well as nearly all tumors related to Lynch syndrome are hallmarked by microsatellite instability (MSI) as a result of a defective mismatch repair system. The functional impact of resulting mutations depends on the...

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Detalles Bibliográficos
Autores principales: Woerner, Stefan M., Yuan, Yan P., Benner, Axel, Korff, Sebastian, von Knebel Doeberitz, Magnus, Bork, Peer
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808963/
https://www.ncbi.nlm.nih.gov/pubmed/19820113
http://dx.doi.org/10.1093/nar/gkp839