Effects of Cytochrome P450 Inhibitors on Itraconazole and Fluconazole Induced Cytotoxicity in Hepatocytes

Itraconazole and fluconazole have been reported to induce hepatotoxicity in patients. The present study was designed to investigate the role of cytochrome P450 inhibitors, SKF 525A, and curcumin pretreatment on the cytotoxicity of antifungal drugs fluconazole and itraconazole. For 3 consecutive days...

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Detalles Bibliográficos
Autores principales: Somchit, Nhareet, Ngee, Chong Sock, Yaakob, Azhar, Ahmad, Zuraini, Zakaria, Zainul Amiruddin
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809023/
https://www.ncbi.nlm.nih.gov/pubmed/20130764
http://dx.doi.org/10.1155/2009/912320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809023/
https://www.ncbi.nlm.nih.gov/pubmed/20130764
http://dx.doi.org/10.1155/2009/912320

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