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Tyrosine phosphorylation of the N-Methyl-D-Aspartate receptor 2B subunit in spinal cord contributes to remifentanil-induced postoperative hyperalgesia: the preventive effect of ketamine

BACKGROUND: Experimental and clinical studies showed that intraoperative infusionof remifentanil has been associated with postoperative hyperalgesia. Previous reports suggested that spinal N-methyl-D-aspartate (NMDA) receptors may contribute to the development and maintenance of opioid-induced hyper...

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Detalles Bibliográficos
Autores principales: Gu, Xiaoping, Wu, Xiaoli, Liu, Yue, Cui, Songqin, Ma, Zhengliang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809057/
https://www.ncbi.nlm.nih.gov/pubmed/20042082
http://dx.doi.org/10.1186/1744-8069-5-76