Methylation associated inactivation of RASSF1A and its synergistic effect with activated K-Ras in nasopharyngeal carcinoma

BACKGROUND: Epigenetic silencing of tumor suppressor genes associated with promoter methylation is considered to be a hallmark of oncogenesis. RASSF1A is a candidate tumor suppressor gene which was found to be inactivated in many human cancers. Although we have had a prelimilary cognition about the...

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Detalles Bibliográficos
Autores principales: Wang, Tao, Liu, Hongli, Chen, Yeshan, Liu, Wei, Yu, Jing, Wu, Gang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809060/
https://www.ncbi.nlm.nih.gov/pubmed/20042089
http://dx.doi.org/10.1186/1756-9966-28-160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809060/
https://www.ncbi.nlm.nih.gov/pubmed/20042089
http://dx.doi.org/10.1186/1756-9966-28-160

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