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Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish development

BACKGROUND: Deconjugation of ubiquitin and/or ubiquitin-like modified protein substrates is essential to modulate protein-protein interactions and, thus, signaling processes in cells. Although deubiquitylating (deubiquitinating) enzymes (DUBs) play a key role in this process, however, their function...

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Detalles Bibliográficos
Autores principales: Tse, William KF, Eisenhaber, Birgit, Ho, Steven HK, Ng, Qimei, Eisenhaber, Frank, Jiang, Yun-Jin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809080/
https://www.ncbi.nlm.nih.gov/pubmed/20040115
http://dx.doi.org/10.1186/1471-2164-10-637