DNA Lesions Induced by Replication Stress Trigger Mitotic Aberration and Tetraploidy Development

During tumorigenesis, cells acquire immortality in association with the development of genomic instability. However, it is still elusive how genomic instability spontaneously generates during the process of tumorigenesis. Here, we show that precancerous DNA lesions induced by oncogene acceleration,...

Descripción completa

Detalles Bibliográficos
Autores principales: Ichijima, Yosuke, Yoshioka, Ken-ichi, Yoshioka, Yoshiko, Shinohe, Keitaro, Fujimori, Hiroaki, Unno, Junya, Takagi, Masatoshi, Goto, Hidemasa, Inagaki, Masaki, Mizutani, Shuki, Teraoka, Hirobumi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809090/
https://www.ncbi.nlm.nih.gov/pubmed/20098673
http://dx.doi.org/10.1371/journal.pone.0008821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809090/
https://www.ncbi.nlm.nih.gov/pubmed/20098673
http://dx.doi.org/10.1371/journal.pone.0008821

Ejemplares similares