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DNA Lesions Induced by Replication Stress Trigger Mitotic Aberration and Tetraploidy Development
During tumorigenesis, cells acquire immortality in association with the development of genomic instability. However, it is still elusive how genomic instability spontaneously generates during the process of tumorigenesis. Here, we show that precancerous DNA lesions induced by oncogene acceleration,...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809090/ https://www.ncbi.nlm.nih.gov/pubmed/20098673 http://dx.doi.org/10.1371/journal.pone.0008821 |