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Augmented B Lymphocyte Response to Antigen in the Absence of Antigen-Induced B Lymphocyte Signaling in an IgG-Transgenic Mouse Line

IgG-containing B cell antigen receptor (IgG-BCR), the BCR mostly expressed on memory B cells, contains a distinct signaling function from IgM-BCR or IgD-BCR expressed on naïve B cells. Because naïve B cells transgenic for IgG exhibit augmented response to antigens similar to memory B cells, the dist...

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Detalles Bibliográficos
Autores principales: Man, Rong-Yong, Onodera, Taishi, Komatsu, Emi, Tsubata, Takeshi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809105/
https://www.ncbi.nlm.nih.gov/pubmed/20098688
http://dx.doi.org/10.1371/journal.pone.0008815