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Intact Cytoskeleton Is Required for Small G Protein Dependent Activation of the Epithelial Na(+) Channel
BACKGROUND: The Epithelial Na(+) Channel (ENaC) plays a central role in control of epithelial surface hydration and vascular volume. Similar to other ion channels, ENaC activity is regulated, in part, by cortical cytoskeleton. Besides, the cytoskeleton is an established target for small G proteins s...
Autores principales: | Karpushev, Alexey V., Ilatovskaya, Daria V., Pavlov, Tengis S., Negulyaev, Yuri A., Staruschenko, Alexander |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809106/ https://www.ncbi.nlm.nih.gov/pubmed/20098689 http://dx.doi.org/10.1371/journal.pone.0008827 |
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