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Time-Resolved and Tissue-Specific Systems Analysis of the Pathogenesis of Insulin Resistance

BACKGROUND: The sequence of events leading to the development of insulin resistance (IR) as well as the underlying pathophysiological mechanisms are incompletely understood. As reductionist approaches have been largely unsuccessful in providing an understanding of the pathogenesis of IR, there is a...

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Detalles Bibliográficos
Autores principales: Kleemann, Robert, van Erk, Marjan, Verschuren, Lars, van den Hoek, Anita M., Koek, Maud, Wielinga, Peter Y., Jie, Annie, Pellis, Linette, Bobeldijk-Pastorova, Ivana, Kelder, Thomas, Toet, Karin, Wopereis, Suzan, Cnubben, Nicole, Evelo, Chris, van Ommen, Ben, Kooistra, Teake
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809107/
https://www.ncbi.nlm.nih.gov/pubmed/20098690
http://dx.doi.org/10.1371/journal.pone.0008817