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S100a9 Knockdown Decreases the Memory Impairment and the Neuropathology in Tg2576 Mice, AD Animal Model

Inflammation, insoluble protein deposition and neuronal cell loss are important features in the Alzheimer's disease (AD) brain. To investigate the regulatory genes responsible for the neuropathology in AD, we performed microarray analysis with APP(V717I)-CT100 transgenic mice, an animal model o...

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Detalles Bibliográficos
Autores principales: Ha, Tae-Young, Chang, Keun-A, Kim, Jeong a, Kim, Hye-Sun, Kim, Seonghan, Chong, Young Hae, Suh, Yoo-Hun
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809116/
https://www.ncbi.nlm.nih.gov/pubmed/20098622
http://dx.doi.org/10.1371/journal.pone.0008840