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Immunoneutralization of TGFβ1 Improves Skeletal Muscle Regeneration: Effects on Myoblast Differentiation and Glycosaminoglycan Content

When injured by crushing, the repair of the slow-twitch soleus rat muscle, unlike the fast-twitch EDL, is associated with fibrosis. As TGFβ1, whose activity can be controlled by glycosaminoglycans (GAG), plays a major role in fibrosis, we hypothesized that levels of TGFβ1 and GAG contents could acco...

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Detalles Bibliográficos
Autores principales: Zimowska, M., Duchesnay, A., Dragun, P., Oberbek, A., Moraczewski, J., Martelly, I.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809363/
https://www.ncbi.nlm.nih.gov/pubmed/20111627
http://dx.doi.org/10.1155/2009/659372