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TBCD Links Centriologenesis, Spindle Microtubule Dynamics, and Midbody Abscission in Human Cells

Microtubule-organizing centers recruit α- and β-tubulin polypeptides for microtubule nucleation. Tubulin synthesis is complex, requiring five specific cofactors, designated tubulin cofactors (TBCs) A–E, which contribute to various aspects of microtubule dynamics in vivo. Here, we show that tubulin c...

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Detalles Bibliográficos
Autores principales: Fanarraga, Mónica López, Bellido, Javier, Jaén, Cristina, Villegas, Juan Carlos, Zabala, Juan Carlos
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809749/
https://www.ncbi.nlm.nih.gov/pubmed/20107510
http://dx.doi.org/10.1371/journal.pone.0008846