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A Novel 3-D Mineralized Tumor Model to Study Breast Cancer Bone Metastasis

BACKGROUND: Metastatic bone disease is a frequent cause of morbidity in patients with advanced breast cancer, but the role of the bone mineral hydroxyapatite (HA) in this process remains unclear. We have developed a novel mineralized 3-D tumor model and have employed this culture system to systemati...

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Detalles Bibliográficos
Autores principales: Pathi, Siddharth P., Kowalczewski, Christine, Tadipatri, Ramya, Fischbach, Claudia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809751/
https://www.ncbi.nlm.nih.gov/pubmed/20107512
http://dx.doi.org/10.1371/journal.pone.0008849