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A Novel 3-D Mineralized Tumor Model to Study Breast Cancer Bone Metastasis
BACKGROUND: Metastatic bone disease is a frequent cause of morbidity in patients with advanced breast cancer, but the role of the bone mineral hydroxyapatite (HA) in this process remains unclear. We have developed a novel mineralized 3-D tumor model and have employed this culture system to systemati...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809751/ https://www.ncbi.nlm.nih.gov/pubmed/20107512 http://dx.doi.org/10.1371/journal.pone.0008849 |