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Creating a Novel Origin of Replication through Modulating DNA-Protein Interfaces

BACKGROUND: While the molecular mechanisms of DNA-protein specificity at the origin of replication have been determined in many model organisms, these interactions remain unknown in the majority of higher eukaryotes and numerous vertebrate viruses. Similar to many viral origins of replication, adeno...

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Detalles Bibliográficos
Autores principales: Hewitt, F. Curtis, Samulski, R. Jude
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809752/
https://www.ncbi.nlm.nih.gov/pubmed/20107513
http://dx.doi.org/10.1371/journal.pone.0008850