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Distinct Type of Transmission Barrier Revealed by Study of Multiple Prion Determinants of Rnq1
Prions are self-propagating protein conformations. Transmission of the prion state between non-identical proteins, e.g. between homologous proteins from different species, is frequently inefficient. Transmission barriers are attributed to sequence differences in prion proteins, but their underlying...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809767/ https://www.ncbi.nlm.nih.gov/pubmed/20107602 http://dx.doi.org/10.1371/journal.pgen.1000824 |