Melanoma Differentiation-Associated Gene 5 (MDA5) Is Involved in the Innate Immune Response to Paramyxoviridae Infection In Vivo

The early host response to pathogens is mediated by several distinct pattern recognition receptors. Cytoplasmic RNA helicases including RIG-I and MDA5 have been shown to respond to viral RNA by inducing interferon (IFN) production. Previous in vitro studies have demonstrated a direct role for MDA5 i...

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Detalles Bibliográficos
Autores principales: Gitlin, Leonid, Benoit, Loralyn, Song, Christina, Cella, Marina, Gilfillan, Susan, Holtzman, Michael J., Colonna, Marco
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809771/
https://www.ncbi.nlm.nih.gov/pubmed/20107606
http://dx.doi.org/10.1371/journal.ppat.1000734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809771/
https://www.ncbi.nlm.nih.gov/pubmed/20107606
http://dx.doi.org/10.1371/journal.ppat.1000734

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