Modification of N-glycosylation sites allows secretion of bacterial chondroitinase ABC from mammalian cells

Although many eukaryotic proteins have been secreted by transfected bacterial cells, little is known about how a bacterial protein is treated as it passes through the secretory pathway when expressed in a eukaryotic cell. The eukaryotic N-glycosylation system could interfere with folding and secreti...

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Detalles Bibliográficos
Autores principales: Muir, Elizabeth M., Fyfe, Ian, Gardiner, Sonya, Li, Li, Warren, Philippa, Fawcett, James W., Keynes, Roger J., Rogers, John H.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science Publishers 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809921/
https://www.ncbi.nlm.nih.gov/pubmed/19900493
http://dx.doi.org/10.1016/j.jbiotec.2009.11.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809921/
https://www.ncbi.nlm.nih.gov/pubmed/19900493
http://dx.doi.org/10.1016/j.jbiotec.2009.11.002

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