Antigen-Specific Dependence of Tr1-Cell Therapy in Preclinical Models of Islet Transplant

OBJECTIVE: In type 1 diabetes, allogeneic pancreatic islet transplant restores insulin production, but life-threatening immunosuppression is required to avoid graft rejection. Induction of antigen (Ag)–specific tolerance by cell therapy with regulatory T-cells (Tregs) represents an attractive altern...

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Detalles Bibliográficos
Autores principales: Gagliani, Nicola, Jofra, Tatiana, Stabilini, Angela, Valle, Andrea, Atkinson, Mark, Roncarolo, Maria-Grazia, Battaglia, Manuela
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809952/
https://www.ncbi.nlm.nih.gov/pubmed/19934002
http://dx.doi.org/10.2337/db09-1168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809952/
https://www.ncbi.nlm.nih.gov/pubmed/19934002
http://dx.doi.org/10.2337/db09-1168

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