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Antigen-Specific Dependence of Tr1-Cell Therapy in Preclinical Models of Islet Transplant

OBJECTIVE: In type 1 diabetes, allogeneic pancreatic islet transplant restores insulin production, but life-threatening immunosuppression is required to avoid graft rejection. Induction of antigen (Ag)–specific tolerance by cell therapy with regulatory T-cells (Tregs) represents an attractive altern...

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Detalles Bibliográficos
Autores principales:	Gagliani, Nicola, Jofra, Tatiana, Stabilini, Angela, Valle, Andrea, Atkinson, Mark, Roncarolo, Maria-Grazia, Battaglia, Manuela
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809952/ https://www.ncbi.nlm.nih.gov/pubmed/19934002 http://dx.doi.org/10.2337/db09-1168

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