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TCF7L2 Variant rs7903146 Affects the Risk of Type 2 Diabetes by Modulating Incretin Action

OBJECTIVE: Common variants in the gene TCF7L2 confer the largest effect on the risk of type 2 diabetes. The present study was undertaken to increase our understanding of the mechanisms by which this gene affects type 2 diabetes risk. RESEARCH DESIGN AND METHODS: Eight subjects with risk-conferring T...

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Detalles Bibliográficos
Autores principales: Villareal, Dennis T., Robertson, Heather, Bell, Graeme I., Patterson, Bruce W., Tran, Hung, Wice, Burton, Polonsky, Kenneth S.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809956/
https://www.ncbi.nlm.nih.gov/pubmed/19934000
http://dx.doi.org/10.2337/db09-1169