Molecular and Metabolic Evidence for Mitochondrial Defects Associated With β-Cell Dysfunction in a Mouse Model of Type 2 Diabetes

OBJECTIVE: The inability of pancreatic β-cells to appropriately respond to glucose and secrete insulin are primary defects associated with β-cell failure in type 2 diabetes. Mitochondrial dysfunction has been implicated as a key factor in the development of type 2 diabetes; however, a link between m...

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Detalles Bibliográficos
Autores principales: Lu, Hongfang, Koshkin, Vasilij, Allister, Emma M., Gyulkhandanyan, Armen V., Wheeler, Michael B.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809957/
https://www.ncbi.nlm.nih.gov/pubmed/19903739
http://dx.doi.org/10.2337/db09-0129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809957/
https://www.ncbi.nlm.nih.gov/pubmed/19903739
http://dx.doi.org/10.2337/db09-0129

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