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A Point Mutation in Sec61α1 Leads to Diabetes and Hepatosteatosis in Mice
OBJECTIVE: Type 2 diabetes is caused by both environmental and genetic factors. To better understand the genetic factors we used forward genetics to discover genes that have not previously been implicated in the development of hyperglycemia or diabetes. RESEARCH DESIGN AND METHODS: Offspring of ethy...
Autores principales: | Lloyd, David J., Wheeler, Matthew C., Gekakis, Nicholas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809972/ https://www.ncbi.nlm.nih.gov/pubmed/19934005 http://dx.doi.org/10.2337/db08-1362 |
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