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Preparation and Characterization of Rodent Intestinal Microsomes: Comparative Assessment of Two Methods
Small intestine plays an important role in the first-pass metabolism of orally ingested xenobiotics as a result of expression of both Phase I and Phase II metabolic enzymes, together with associated transporters. Intestinal microsomes thus can be used to study susceptibility of compounds to metaboli...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810057/ https://www.ncbi.nlm.nih.gov/pubmed/20177465 http://dx.doi.org/10.4103/0250-474X.51968 |