Antiplasmodial Activities of Homogentisic Acid Derivative Protein Kinase Inhibitors Isolated from a Vanuatu Marine Sponge Pseudoceratina sp.

As part of our search for new antimalarial drugs in South Pacific marine sponges, we have looked for inhibitors of Pfnek-1, a specific protein kinase of Plasmodium falciparum. On the basis of promising activity in a preliminary screening, the ethanolic crude extract of a new species of Pseudoceratin...

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Detalles Bibliográficos
Autores principales: Lebouvier, Nicolas, Jullian, Valérie, Desvignes, Isabelle, Maurel, Séverine, Parenty, Arnaud, Dorin-Semblat, Dominique, Doerig, Christian, Sauvain, Michel, Laurent, Dominique
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810230/
https://www.ncbi.nlm.nih.gov/pubmed/20098604
http://dx.doi.org/10.3390/md7040640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810230/
https://www.ncbi.nlm.nih.gov/pubmed/20098604
http://dx.doi.org/10.3390/md7040640

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