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Antiplasmodial Activities of Homogentisic Acid Derivative Protein Kinase Inhibitors Isolated from a Vanuatu Marine Sponge Pseudoceratina sp.
As part of our search for new antimalarial drugs in South Pacific marine sponges, we have looked for inhibitors of Pfnek-1, a specific protein kinase of Plasmodium falciparum. On the basis of promising activity in a preliminary screening, the ethanolic crude extract of a new species of Pseudoceratin...
Autores principales: | Lebouvier, Nicolas, Jullian, Valérie, Desvignes, Isabelle, Maurel, Séverine, Parenty, Arnaud, Dorin-Semblat, Dominique, Doerig, Christian, Sauvain, Michel, Laurent, Dominique |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810230/ https://www.ncbi.nlm.nih.gov/pubmed/20098604 http://dx.doi.org/10.3390/md7040640 |
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